Anti-SPIN1 Antibody

Raised in Rabbit as a polyclonal reagent against human SPIN1 (Spindlin 1), this unconjugated primary antibody from Antibodies.com is supplied in a 100 µl vial and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows. SPIN1 is a nuclear histone code reader that contains three Tudor-like domains and recognizes trimethylated histone H3 lysine 4 (H3K4me3), linking chromatin state to active ribosomal RNA transcription, meiotic progression in oocytes, and the Wnt/β-catenin signaling cascade. Researchers studying tumor biology use this reagent because SPIN1 overexpression has been documented in ovarian, hepatocellular, and non-small cell lung carcinoma tissues, supporting applications in cancer pathology and chromatin regulation research. The antibody should be stored at -20 °C in working aliquots to limit freeze-thaw cycles and preserve activity across repeated experiments.