Anti-SPDEF Antibody

A polyclonal rabbit host antibody targeting SPDEF (SAM Pointed Domain Containing ETS Transcription Factor), offered unconjugated by Antibodies.com for western blot and immunohistochemistry workflows on human samples. The reagent is supplied in a single-use vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, packaged as a 100 µl volume that supports multiple blots and staining runs.

SPDEF, originally characterized as Prostate-Derived ETS Factor, is studied as a regulator of epithelial differentiation in prostate, breast, and gastric tissues, and is implicated in goblet cell gene expression programs relevant to mucosal biology and colorectal adenocarcinoma research. Researchers profiling luminal versus basal prostate markers, examining ETS-family transcription factor activity in hormone-driven cancers, or validating SPDEF knockdown and overexpression phenotypes will find this antibody applicable to detecting endogenous protein in whole-cell lysates and formalin-fixed paraffin-embedded tissue sections.

Aliquot upon receipt and store at -20°C to limit freeze-thaw cycles of the glycerol-stabilized stock solution.