Anti-SPARC Antibody

This polyclonal primary antibody from Antibodies.com targets SPARC (Secreted Protein Acidic and Rich in Cysteine), a calcium-binding matricellular glycoprotein also known as osteonectin or BM-40 that modulates collagen deposition, cell-matrix adhesion, wound healing, and tumor-stroma crosstalk. Raised in rabbit and supplied as an unconjugated 100 µl vial aliquot, the reagent is validated for western blot and immunohistochemistry applications on human, mouse, and rat specimens. It is recommended for storage at -20 °C in working aliquots to limit freeze-thaw cycles and preserve reagent performance across repeated use. Investigators studying fibrosis, osteogenesis, melanoma metastasis, or angiogenesis routinely deploy this antibody to localize SPARC expression in tissue sections and to detect the endogenous protein in cell lysates, supporting both qualitative and semi-quantitative readouts of matricellular signaling in basic and translational research.