Anti-SPARC Antibody

Rabbit polyclonal antibody from Antibodies.com targeting SPARC (Secreted Protein Acidic and Rich in Cysteine), a matricellular glycoprotein central to extracellular matrix turnover, cell migration, and tumor-stroma crosstalk. Supplied as 100 µl of unconjugated antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the reagent is intended for Western blot detection of endogenous SPARC in human, mouse, and rat samples. SPARC, also known as osteonectin or BM-40, is routinely investigated as a marker of activated fibroblasts and reactive stroma in fibrosis, wound healing, and cancer invasion models, where polyclonal coverage offers broader epitope recognition across denatured lysates. The unconjugated format integrates cleanly with standard HRP- or fluorophore-conjugated secondary detection workflows for immunoblotting of cell line and tissue-derived lysates.