Anti-SPAG5 Antibody

SPAG5 (Sperm Associated Antigen 5), also known as Astrin, is a microtubule-associated protein essential for mitotic chromosome alignment, kinetochore-microtubule attachment, and spindle assembly checkpoint signaling. This rabbit polyclonal antibody from Antibodies.com is raised against human SPAG5 and supplied as 100 µL of unconjugated antiserum validated for Western blot and immunofluorescence applications. The reagent detects endogenous SPAG5 in human cell lines, supporting studies of mitotic progression, Aurora A kinase pathway analysis, and investigation of SPAG5 overexpression reported in cancers such as breast, lung, and hepatocellular carcinoma. Researchers use the antibody to examine centrosome function, cytokinesis, and chromosome segregation fidelity in dividing cells.