Anti-Sp4 Antibody

Targeting the Sp4 transcription factor, this rabbit polyclonal reagent from Antibodies.com belongs to the Sp/KLF family of zinc finger DNA-binding proteins that regulate GC-rich promoters across many cell types. The antibody is supplied as an unconjugated polyclonal preparation raised in rabbit and validated for western blot and immunohistochemistry workflows, enabling detection of endogenous Sp4 in lysates and localization of Sp4 expression in fixed tissue sections. Because the reagent cross-reacts with human, mouse, and rat samples, it is well suited to translational studies that span cultured human cell lines and rodent disease models, including work on Sp4's documented roles in hippocampal development, enamel biomineralization, and psychiatric-disorder-associated gene-regulatory programs.

Shipped at 100 µl per vial, the antibody is intended for dilute use in standard immunoblotting and chromogenic IHC protocols. Investigators studying transcription-factor networks, neural stem-cell differentiation, or Sp-family target-gene regulation frequently apply this reagent as a primary detection tool. Antibodies.com provides the supporting quality-control documentation, and the unconjugated format allows end-users to couple the antibody to HRP, fluorophores, or biotin depending on assay design. Refrigerated storage preserves activity for long-term bench use, with aliquoting recommended to limit freeze-thaw cycles.