Anti-SP-A Antibody

This rabbit polyclonal antibody from Antibodies.com targets Surfactant Protein A (SP-A), a hydrophilic collectin secreted by type II alveolar epithelial cells and a core component of the pulmonary surfactant system that lowers alveolar surface tension. Beyond its biophysical role, SP-A participates in pulmonary innate immunity through opsonization of inhaled pathogens and modulation of inflammatory cell activity, supporting research into respiratory biology, neonatal respiratory distress syndrome, and models of acute lung injury. The reagent is raised in rabbit, supplied as an unconjugated IgG preparation in a 100 µl volume, and validated for Western blot and ELISA workflows on human, mouse, and rat samples. Because SP-A abundance shifts in idiopathic pulmonary fibrosis, alveolar proteinosis, and several infectious lung diseases, this polyclonal reagent permits comparative protein detection across multiple species in cell lysates and tissue homogenates without the species restrictions often encountered with monoclonal alternatives.