Anti-Sox2 Antibody

Sox2 (Sex Determining Region Y-Box 2) is a master transcription factor essential for maintaining pluripotency in embryonic stem cells and neural progenitor populations. This mouse monoclonal reagent from Antibodies.com supports research into stem cell maintenance, neurodevelopment, and oncology, where Sox2 expression is a defining marker for cancer stem cells in gliomas, squamous cell carcinomas, and small-cell lung cancer.

The unconjugated antibody is provided as a 100 µL purified preparation in 0.1M Tris-Glycine buffer (pH 7.4) with 150 mM NaCl, 0.2% sodium azide, and 50% glycerol as a cryoprotectant. Validated for Western blot (WB), immunocytochemistry (ICC), and flow cytometry (FC), the reagent performs reliably across protein-level detection, subcellular localization, and single-cell suspension workflows.

Reactivity has been confirmed in human and mouse samples, enabling cross-species studies in pluripotency and developmental biology models. Monoclonal clonality delivers batch-to-batch reproducibility and consistent epitope recognition across experimental replicates.