Anti-SORT1 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets SORT1 (Sortilin 1), a multi-ligand type-I transmembrane receptor involved in protein trafficking, lysosomal enzyme sorting, and neurotensin signaling. Supplied as a 100 µl aliquot in an unconjugated format, the reagent is validated for western blot and immunohistochemistry workflows and enables detection of endogenous Sortilin 1 in lysates and tissue sections from human, mouse, and rat samples. The polyclonal antibody is raised in rabbit and recognizes both native and denatured epitopes of the target protein, which is widely expressed in neuronal, hepatic, and adipose tissues. Investigators studying neurodegeneration, lipid metabolism, and receptor-mediated endocytosis use this reagent to map Sortilin 1 distribution and to characterize its interactions with ligands such as progranulin and neurotensin. To preserve activity over multiple experiments, aliquot the vial on receipt and limit repeated freeze-thaw cycles.