Anti-SOD2 Antibody

Superoxide dismutase 2 (SOD2), also called manganese superoxide dismutase (MnSOD), is a mitochondrial matrix enzyme that catalyzes the conversion of superoxide radicals into hydrogen peroxide and molecular oxygen, forming a frontline defense against oxidative stress generated by the electron transport chain. This polyclonal reagent is raised in rabbit, supplied as an unconjugated 100 µl volume, and validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples. The polyclonal format recognizes multiple epitopes on the SOD2 homotetramer, supporting reliable detection of endogenous protein in cell lysates, tissue homogenates, and fixed sections. Antibodies.com positions the reagent as a flexible tool for cell biology, neuroscience, and cancer research programs where mitochondrial redox homeostasis is a focus, including studies of oxidative damage pathways, age-related degeneration, and tumor metabolism in which altered SOD2 expression frequently accompanies disease progression. The unconjugated format allows researchers to couple the antibody to their preferred fluorophore or enzyme reporter for custom detection assays, and the 100 µl pack supports multiple replicate experiments across membranes and slides.