Anti-SOCS-1 Antibody

SOCS-1 (Suppressor of Cytokine Signaling 1) is a key negative feedback regulator of the JAK/STAT cytokine signaling pathway, and this unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the SOCS-1 target for use in Western blot and ELISA workflows. The reagent is supplied as 100 µl of polyclonal antisera and has been validated for detection of SOCS-1 in human, mouse, and rat samples. SOCS-1 plays a central role in shutting down interferon, interleukin, and growth factor responses, and altered SOCS-1 expression is widely studied in models of chronic inflammation, autoimmunity, and tumor immune evasion. Researchers commonly use this reagent to monitor SOCS-1 induction following cytokine stimulation, to probe STAT phosphorylation dynamics, and to assess suppressor-of-cytokine-signaling family expression in cell lysates and tissue homogenates. Aliquot upon receipt and store at -20 °C for long-term stability, avoiding repeated freeze-thaw cycles to preserve antibody activity.