Anti-SNX12 Antibody

This rabbit polyclonal antibody targets SNX12 (Sorting Nexin 12), a PX domain-containing endosomal trafficking protein that participates in cargo sorting between early endosomes and the trans-Golgi network. The unconjugated reagent is supplied as a 100 µl aliquot and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows in human samples.

SNX12 belongs to the sorting nexin family of peripheral membrane proteins, where it binds phosphoinositide lipids through its PX domain and contributes to retromer-associated retrograde transport pathways. Researchers studying endocytic recycling, lysosomal biogenesis, and autophagy regulation frequently probe SNX12 expression to map its distribution across tissue sections and to follow its recruitment to endosomal microdomains.

Manufactured by Antibodies.com as a polyclonal reagent raised in rabbit, the antibody recognizes human SNX12 and is provided unconjugated, allowing flexible pairing with secondary labels such as HRP, Alexa Fluor, or biotin conjugates depending on the detection chemistry chosen. Routine storage at 4 °C in the supplied buffer preserves activity for several months, with aliquoting recommended for longer-term use and to limit freeze-thaw cycles.