Anti-SNRPD3 Antibody

Produced in rabbit as a polyclonal reagent, this unconjugated IgG antibody targets SNRPD3, the small nuclear ribonucleoprotein D3 polypeptide that forms part of the Sm protein ring encircling snRNAs within U1, U2, U4/U6, and U5 spliceosomal small nuclear ribonucleoproteins. SNRPD3 localizes primarily to nuclear speckles and Cajal bodies, where it contributes to pre-mRNA splicing machinery assembly. Manufactured by Antibodies.com for research use, the antibody is supplied as a 200µl volume and has been validated for Western Blot (WB), Immunohistochemistry (IHC), and Flow Cytometry (FC) workflows against human samples. The unconjugated format supports flexible secondary antibody pairing and downstream detection chemistries, including fluorescent, chromogenic, or HRP-based readouts depending on the experiment. Suitable for single-use aliquoting to preserve reagent integrity across repeated freeze-thaw cycles, this primary antibody is intended for laboratories characterizing spliceosome composition, snRNP biogenesis, or autoantibody reactivity associated with systemic autoimmune conditions such as systemic lupus erythematosus, where anti-Sm antibodies frequently recognize SNRPD3 alongside SNRPD1 and SNRPD2.