Anti-SNRPD2 Antibody

Raised in rabbit against SNRPD2, this unconjugated polyclonal reagent recognizes the D2 polypeptide of the small nuclear ribonucleoprotein complex that drives pre-mRNA splicing. SNRPD2 is a core building block of the U1, U2, U4/U6, and U5 snRNPs and concentrates in the nucleus, including Cajal bodies and nuclear speckles, where spliceosome assembly takes place.

From Antibodies.com, the antibody is supplied as 100 µl of a 1 mg/ml stock prepared in PBS with 0.1% sodium azide and 50% glycerol. The 50% glycerol content acts as a cryoprotectant, and the inclusion of 0.1% sodium azide helps prevent microbial contamination during routine use. The buffer composition permits direct dilution into common immunodetection workflows without further preparation.

The reagent has been validated for Western blot, immunohistochemistry, and immunofluorescence applications, and it shows reactivity with human, mouse, and rat samples, giving laboratories flexibility to compare SNRPD2 expression across standard experimental models. Researchers investigating spliceosome biogenesis, snRNP assembly, RNA processing, or subnuclear organization can use this antibody to probe target expression in cell lysates, fixed tissue sections, and cultured cell preparations.