Anti-SNRPD2 Antibody

The SNRPD2 protein, also known as Small Nuclear Ribonucleoprotein D2, forms part of the heptameric Sm ring that loads onto U1, U2, U4, U5, and U6 spliceosomal snRNPs, making it a core building block of the pre-mRNA splicing machinery. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com was raised against SNRPD2 and is validated for western blot (WB), immunohistochemistry (IHC), and flow cytometry (FC) applications on human specimens. The antibody is supplied as 100 µl of polyclonal antiserum and detects endogenous SNRPD2 in cell lysates, formalin-fixed tissue sections, and dissociated cell populations. Investigators working on spliceosome assembly, snRNP biogenesis, spinal muscular atrophy-linked SMN complex function, and splicing-factor dysregulation in oncology and neurodegeneration use SNRPD2 immunodetection to track Sm-ring integrity and to probe changes in spliceosomal composition under stress, differentiation, or disease conditions.