Anti-SNRPA Antibody

SNRPA encodes the 28 kDa polypeptide A subunit of the U1 small nuclear ribonucleoprotein complex, the ribonucleoprotein particle responsible for recognising the 5' splice site during pre-mRNA splicing in eukaryotic nuclei. The Antibodies.com rabbit polyclonal reagent is affinity-purified against SNRPA and supplied unconjugated in a 100 µl vial, ready for direct labelling with fluorophore- or enzyme-conjugated secondaries.

Recommended applications include Western blot and immunohistochemistry on human and mouse specimens, supporting laboratories studying spliceosome biogenesis, U1 snRNP assembly, and the redistribution of splicing factors under cellular stress or differentiation. The polyclonal format broadens epitope coverage across the SNRPA primary sequence, increasing the chance of detecting multiple processed isoforms or post-translationally modified forms. Researchers commonly combine SNRPA detection with SNRNP70 antibodies to characterise U1 RNP composition. This product is intended for research use only and should be stored refrigerated with aliquoting to limit freeze-thaw cycles.