Anti-SMYD2 Antibody

SMYD2 (SET and MYND domain-containing protein 2) is a lysine methyltransferase that targets histone H3K36 and non-histone substrates including p53 and ERα, contributing to transcriptional regulation and chromatin remodeling in eukaryotic cells. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against SMYD2 and validated for Western blot and ELISA workflows against human, mouse, and rat samples. Supplied as 100 µl of liquid antiserum, the reagent is stored refrigerated at 2-8 degrees C and pairs readily with HRP- or fluorophore-conjugated secondary antibodies. Researchers studying SET-domain methyltransferase activity, tumor suppressor methylation, or epigenetic mechanisms in cardiac and cancer biology use SMYD2-specific polyclonal reagents to monitor endogenous expression by immunoblotting whole-cell lysates and to probe evolutionary conserved regions across species. The polyclonal format offers broader epitope coverage than a monoclonal clone, an advantage when detecting lower-abundance targets in tissue extracts or when mapping post-translational methylation marks on chromatin-associated factors.