Anti-SMYD2 Antibody

SMYD2 is a SET and MYND domain-containing lysine methyltransferase that catalyzes methylation of histone H3 at lysines 4 and 36, and also modifies non-histone substrates including p53, retinoblastoma protein, and HSP90. This Rabbit polyclonal antibody from Antibodies.com is validated for Western blot and immunohistochemistry workflows, enabling investigation of SMYD2 expression and post-translational regulation in Human, Mouse, and Rat tissue or cell samples. The unconjugated reagent is supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a buffer formulation compatible with storage at -20°C and resistant to repeated freeze-thaw cycles. Researchers studying esophageal squamous cell carcinoma, acute myeloid leukemia, cardiac development, or skeletal muscle differentiation frequently probe SMYD2 abundance to link methyltransferase activity to chromatin remodeling and tumor suppressor methylation. Polyclonal reactivity across three species makes this reagent useful for cross-species comparative studies and for verifying antibody specificity in knockout or transgenic model systems used in basic and translational research.