Anti-SMYD2 Antibody

Raised in rabbit against the SET and MYND domain-containing protein 2, this unconjugated polyclonal reagent from Antibodies.com is validated for western blot detection of SMYD2 in human and mouse samples. SMYD2 is a lysine methyltransferase that targets both histone substrates such as H3K36 and non-histone substrates including p53 (at K370), RB1, and estrogen receptor alpha, linking it to transcriptional regulation, chromatin modification, and cancer biology research.

Supplied as 200 µl of polyclonal serum with an IgG isotype, the antibody is intended for research use only and fits standard immunoblotting workflows that resolve the target near its expected molecular weight. The unconjugated format allows researchers to pair the reagent with their preferred secondary antibody and detection chemistry, supporting flexibility across experimental designs that probe SMYD2 expression, methylation activity, and downstream signaling in cell and tissue lysates.