Anti-SMUG1 Antibody

SMUG1 (Single-Strand Selective Monofunctional Uracil-DNA Glycosylase 1) is a key enzyme in the base excision repair pathway, responsible for excising uracil residues from single-stranded and double-stranded DNA. This polyclonal antibody, raised in rabbit, recognizes endogenous SMUG1 protein and has been validated for Western blot, immunohistochemistry, and immunocytochemistry applications across human, mouse, and rat samples. Supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at pH 7.2, the unconjugated antibody offers flexibility for downstream labeling and detection workflows. Researchers investigating genomic stability, DNA damage response, and base excision repair mechanisms can use this reagent to probe SMUG1 expression in tissue sections, cultured cells, and lysate preparations. The rabbit polyclonal format allows recognition of multiple epitopes on the target, increasing the likelihood of strong signal even when a single epitope is partially masked by fixation or sample processing. For research use only, the 100 µl vial from Antibodies.com provides ample material for multiple experimental setups.