Anti-SMPX Antibody

This polyclonal antibody from Antibodies.com targets SMPX (Small Muscle Protein, X-linked), an actin-associated cytoskeletal protein encoded on the X chromosome that is highly expressed in skeletal and cardiac muscle. The reagent is raised in rabbit and supplied as an unconjugated preparation in a 100 µl vial, allowing flexibility in downstream labeling and detection chemistry.

Mutations in SMPX have been associated with DFNX4, an X-linked form of progressive non-syndromic hearing loss, and the protein has been studied for its role in stress fiber bundling and muscle cytoskeletal remodeling. Researchers working on auditory neuroscience, skeletal muscle physiology, and cytoskeletal organization use anti-SMPX reagents to probe expression and subcellular distribution in human tissues and cultured cells.

Validated applications include Western blot and immunofluorescence, supporting both immunoblot-based quantification and visualization of endogenous SMPX in fixed cells or tissue sections. The antibody is reactive with human SMPX. Storage recommendations from the supplier call for refrigerated handling in working aliquots to preserve activity over multiple experiments.