Anti-SMCHD1 Antibody

This polyclonal antibody targets SMCHD1, a chromatin-associated ATPase best known for its role in maintaining X-chromosome inactivation and regulating repetitive elements across the genome. Raised in rabbit, the reagent is supplied by Antibodies.com in a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, ready for short-term storage at 4°C and longer-term storage at -20°C. The unconjugated IgG fraction is validated for western blot, immunohistochemistry, and immunofluorescence workflows and shows reactivity against human, mouse, and rat samples, supporting translational studies that span rodent disease models and human patient tissue. Researchers working on facioscapulohumeral muscular dystrophy, epigenetic silencing, or D4Z4 repeat regulation will find this reagent useful for probing endogenous SMCHD1 distribution in fixed sections, lysates, and cultured cells. Sodium azide is included as a preservative; samples should be protected from light and handled with standard laboratory precautions.