Anti-SMC2 Antibody

This rabbit polyclonal antibody from Antibodies.com targets SMC2, a core subunit of the condensin complex that drives chromosome condensation and segregation during mitosis. The unconjugated IgG reagent is supplied as a 100 µl volume and validated for Western blot detection of endogenous human SMC2 protein in cell lysates.

Research context: SMC2 pairs with SMC4 to form the structural backbone of condensin I and condensin II, which scaffold mitotic chromosomes and support faithful segregation of sister chromatids. Probing SMC2 expression is relevant to studies of cell cycle regulation, mitotic chromosome architecture, DNA damage response, and oncology, where condensin dysregulation has been linked to aneuploidy and tumor progression.

Specifications:

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Conjugate: Unconjugated
• Reactivity: Human
• Target: SMC2 (Structural Maintenance of Chromosomes 2)
• Application: Western blot (WB)
• Format: 100 µl vial

This unconjugated primary antibody is suited to laboratories characterizing condensin complex assembly, mapping mitotic chromosome organization, or screening cancer cell lines for altered SMC2 levels, and is intended for research use only.