Anti-SMARCE1 Antibody

An affinity-purified polyclonal reagent from Antibodies.com that targets SMARCE1, the chromatin-remodeling subunit also known as BAF57 within the SWI/SNF ATP-dependent complex. The unconjugated antibody is supplied as 100 µL per vial and is reactive against human, mouse, and rat antigens, supporting cross-species work in cancer biology, steroid receptor signaling, and Coffin–Siris syndrome models. Researchers employ this reagent in chromatin immunoprecipitation experiments to map BAF57 occupancy at promoter and enhancer regions, in western blot workflows to verify subunit composition of BAF complexes, in immunofluorescence to visualize nuclear localization, in immunoprecipitation for pull-down of intact SWI/SNF assemblies, and in immunohistochemistry of tumor sections where SMARCE1 status carries diagnostic relevance—most clearly in clear cell meningioma, a WHO-recognized subtype in which biallelic SMARCE1 inactivation is a defining molecular event.