Anti-SMAD9 Antibody

SMAD9 (also called SMAD8) operates as a receptor-regulated signal transducer within the BMP branch of the TGF-β superfamily, forming complexes with SMAD4 to regulate bone morphogenetic protein–driven gene transcription.

This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against human SMAD9 and validated for Western blot and immunofluorescence detection in human samples. Each vial contains 200 µl of antibody suitable for probing endogenous SMAD9 expression in cell lysates, fixed sections, and transfected mammalian cell lines.

The reagent supports investigation of BMP-mediated osteogenic differentiation, vascular development, and hereditary hemorrhagic telangiectasia–associated signaling, where SMAD9 loss-of-function variants have been reported in the literature.