Anti-Smad2 Antibody

Supplied as a 100 µl aliquot of mouse monoclonal IgG1, this unconjugated primary antibody from Antibodies.com targets Smad2, a key intracellular transducer of TGF-beta signaling. The reagent is validated for Western blot and immunocytochemistry on human samples, supporting studies of canonical SMAD-mediated transcription downstream of activin, nodal, and TGF-beta receptors. Investigators working on colorectal, pancreatic, and hepatocellular carcinoma models, as well as fibrotic and epithelial-mesenchymal transition research, use Smad2 immunoblotting and immunostaining to monitor receptor-driven C-terminal phosphorylation and nuclear translocation. Host species is mouse, clonality monoclonal, isotype IgG1, with no fluorophore or enzyme conjugate attached, allowing flexible secondary antibody pairing for chemiluminescent WB or fluorescence ICC workflows.