Anti-Smad1 (phospho-S187) Antibody

Raised in rabbit as an unconjugated polyclonal, this phospho-specific reagent from Antibodies.com selectively recognizes Smad1 only when phosphorylated at serine 187, a modification introduced at the C-terminal MH2 region by activated type I BMP receptors. Because binding depends on the phospho-residue, the antibody reports active BMP pathway engagement rather than bulk Smad1 abundance, supporting studies of signal onset, attenuation, and compartment-specific activation in cell signalling research.

Supplied as 100 µL of a 1 mg/ml stock in phosphate buffered saline (PBS), pH 7.2, with 0.05% sodium azide as a preservative, the antibody is validated for western blot, immunohistochemistry, immunocytochemistry, and immunoprecipitation across human, mouse, and rat samples. For routine handling, aliquot upon receipt to limit freeze-thaw cycles and preserve phospho-epitope recognition through repeated use.