Anti-SMAD1 Antibody

SMAD1 is a receptor-regulated signal transducer in the BMP (bone morphogenetic protein) signaling cascade, phosphorylated by BMP type I receptors and partnering with SMAD4 to translocate into the nucleus and drive transcription of target genes involved in osteoblast differentiation, chondrogenesis, and neural patterning.

This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes endogenous SMAD1 in human, mouse, and rat samples and has been validated for western blot, immunohistochemistry, and immunofluorescence workflows. The 100 µl volume is sized for routine immunostaining panels and multiple blot reprobes.

Researchers studying BMP-driven bone formation, vascular remodeling linked to pulmonary arterial hypertension, and early developmental signaling can use this antibody to monitor receptor-mediated SMAD1 phosphorylation status and downstream transcriptional responses across cell culture lysates and tissue-derived samples.