Anti-SLP-76 (phospho-Y128) Antibody

The SLP-76 adapter protein, when phosphorylated at tyrosine 128, marks an early signaling event downstream of T-cell receptor engagement. This polyclonal reagent from Antibodies.com was raised in rabbit and affinity-purified to recognize the phosphorylated Y128 epitope selectively, enabling researchers to track activation-dependent modification of SLP-76 in primary lymphocytes and transfected cell systems.

Supplied as 100 µl of unconjugated antibody at 1 mg/ml in phosphate buffered saline (pH 7.2) with 0.05% sodium azide as a preservative, the reagent is validated for Western blot and has been confirmed to react with human, mouse, and rat samples. It is commonly deployed to probe signaling cascades involving LAT, ZAP-70, Itk, and PLC-γ1, supporting studies of thymocyte development, peripheral T-cell responses, and immune checkpoint research.

Each lot is quality-tested by the supplier, and the format suits both standard immunoblotting protocols and immunoprecipitation workflows when combined with appropriate secondary reagents.