Anti-SLCO1C1 Antibody

SLCO1C1 (Solute Carrier Organic Anion Transporter Family Member 1C1), also designated OATP1C1 or OATP-F, functions as a high-affinity thyroid hormone (T4) transporter at the blood-brain barrier, mediating substrate uptake into neuronal and glial cells where it influences CNS development and metabolism. This Antibodies.com polyclonal reagent is raised in rabbit, isotyped as IgG, and supplied unconjugated in a 200 µl liquid format suitable for immunoblotting workflows. The antibody is validated for Western Blot detection of human SLCO1C1 and is used to characterize expression in cell line lysates, primary neural tissue, and recombinant overexpression systems. Recommended handling includes brief equilibration to room temperature before use, storage refrigerated between aliquots to limit freeze-thaw cycles, and standard reducing SDS-PAGE separation prior to transfer onto nitrocellulose or PVDF membranes. With polyclonal coverage across multiple epitopes of the transporter, researchers can apply this reagent to studies of thyroid hormone signaling in the brain, transporter regulation in disease models, and substrate specificity profiling of the OATP family.