Anti-SLC8B1 Antibody

SLC8B1 (solute carrier family 8 member B1), also known as NCLX or NCKX6, is a mitochondrial sodium/calcium exchanger located in the inner mitochondrial membrane. It mediates calcium efflux from the mitochondrial matrix, shaping cytosolic calcium transients and supporting cellular bioenergetics in excitable and metabolically active tissues.

This rabbit polyclonal, unconjugated reagent from Antibodies.com is raised against human SLC8B1 and is supplied as a 100 µl liquid aliquot. It is validated for western blot and immunohistochemistry applications on human samples. The polyclonal format increases the chance of recognizing multiple epitopes on the endogenous protein, supporting detection in cell lysates and fixed tissue sections.

Investigators studying mitochondrial calcium handling, cardiac excitation-contraction coupling, neuronal calcium signaling, or metabolic stress responses use this reagent to track SLC8B1 expression and subcellular distribution. Because it is supplied unconjugated, the antibody can be paired with a user-selected secondary reagent, giving flexibility over detection chemistry and label choice. Store refrigerated; aliquot to limit freeze-thaw cycles and preserve antibody activity across repeated experiments.