Anti-SLC5A6 Antibody

The SLC5A6 gene encodes a sodium-dependent multivitamin transporter (SMVT) that mediates cellular uptake of biotin, pantothenate, and lipoate across the plasma membrane, and it has been investigated in the context of inherited multivitamin transport defects. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against the human SLC5A6 target and supplied as 100 µl of liquid stock, ready to be diluted into standard immunodetection buffers.

The reagent is validated for Western blot (WB) and immunofluorescence (IF) workflows on human samples, supporting detection of endogenous transporter protein in cultured cell lines as well as in fixed tissue sections. Because the antibody is polyclonal, it recognizes multiple epitopes on SLC5A6, which improves signal robustness on both denaturing immunoblots and fixed-cell fluorescence preparations. The unconjugated format leaves detection chemistry open, so end users can pair it with HRP-conjugated secondary antibodies for chemiluminescent WB or with fluorophore-labeled secondary antibodies for confocal or wide-field IF imaging.

Typical research applications include characterization of biotin and pantothenate transport kinetics, knockdown or overexpression studies of SMVT in epithelial and intestinal models, and immunohistochemistry-style IF surveys of SLC5A6 distribution at the plasma membrane. For handling, aliquot upon arrival and store at -20°C, avoiding repeated freeze-thaw cycles to preserve binding activity. For research use only, not intended for diagnostic or therapeutic applications.