Anti-SLC5A5 Antibody

The SLC5A5 gene encodes the sodium-iodide symporter (NIS), an integral plasma membrane glycoprotein that actively transports iodide into thyroid follicular cells and is essential for thyroid hormone biosynthesis. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human SLC5A5 and validated for Western blot and immunohistochemistry workflows on human specimens.

Supplied as a 100 µl liquid aliquot, the antiserum supports studies of iodide uptake regulation, thyroid differentiation, and thyroid oncology, where NIS status is widely used as a tissue marker. Researchers can apply the antibody to assess expression in normal thyroid follicular epithelium, differentiated thyroid carcinomas, and lactating mammary tissue, where NIS is also physiologically expressed.

For best results, store refrigerated in small working aliquots to minimize freeze-thaw cycles and preserve reactivity across repeated experiments. The unconjugated format offers flexibility in choosing secondary reagents for fluorescence, chromogenic, or chemiluminescent detection systems in immunostaining and immunoblotting protocols.