Anti-SLC33A1 Antibody

Raised in rabbit against the SLC33A1 acetyl-CoA transporter, this polyclonal IgG reagent from Antibodies.com is supplied as 50 µl of unconjugated serum suitable for western blot detection of the endogenous endoplasmic reticulum membrane transporter in mouse, rat, and human samples. The antibody recognizes the AT-1 protein product of the SLC33A1 locus, which mediates acetyl-CoA import into the ER lumen and supports luminal acetylation reactions, including N-glycan processing and the acetylation of nascent secretory pathway proteins. Because SLC33A1 expression is tightly linked to cellular metabolism and has been investigated in studies of neurodegenerative disease and ER stress signaling, it is a relevant marker for researchers working on acetyl-CoA homeostasis, membrane transporter regulation, or endoplasmic reticulum biochemistry. Standard western blot protocols using HRP-conjugated secondary antibodies and chemiluminescent detection are recommended for visualizing the band at the expected molecular weight range typical of multi-pass membrane proteins.