Anti-SLC30A2 Antibody

For researchers studying zinc homeostasis and mammary gland biology, this rabbit polyclonal antibody from Antibodies.com targets the SLC30A2 (ZnT2) zinc transporter and is supplied as 100 µl at 1 mg/ml in PBS containing 0.05% sodium azide at approximately pH 7.3.

SLC30A2 is a member of the SLC30 family of zinc efflux transporters and is best characterized for sequestering cytoplasmic zinc into the secretory pathway of mammary epithelial cells, where it loads zinc into milk. Loss-of-function variants in SLC30A2 have been linked to transient neonatal zinc deficiency, making this transporter a focus of investigation into lactation, infant nutrition, and cellular metal handling.

The unconjugated reagent is validated for Western blot and cross-reacts with Human, Mouse, and Rat samples, supporting comparative studies across model systems and patient-derived tissue. Investigators use anti-SLC30A2 antibodies to probe ZnT2 expression in mammary gland, pancreatic islets, prostate epithelium, and selected neuronal populations, and to study how altered zinc compartmentalization contributes to metabolic, developmental, and neurodegenerative phenotypes.

Store at -20 °C in single-use aliquots to limit freeze-thaw cycles, and keep working stocks on ice during benchtop handling; the included sodium azide prevents microbial contamination for routine use. This polyclonal reagent offers epitope-spread coverage that is useful for detecting conserved regions of ZnT2 across species, and is suited to immunoblotting of cell lysates and tissue homogenates.