Anti-SLC29A1 Antibody

This polyclonal IgG reagent from Antibodies.com targets SLC29A1 (equilibrative nucleoside transporter 1, ENT1), a plasma membrane glycoprotein that mediates the facilitated diffusion of nucleosides and nucleoside analog drugs across cell membranes. Raised in rabbit and supplied as an unconjugated preparation in 100 µl, the antibody is validated for Western blot and immunohistochemistry workflows on human tissue specimens. SLC29A1 expression is broadly distributed across epithelial, neuronal, and hematopoietic lineages, and the transporter is studied for its role in adenosine uptake, purinergic signaling, and the cellular disposition of antimetabolite chemotherapeutics such as gemcitabine and cytarabine. Researchers investigating nucleoside salvage pathways, transporter pharmacology, or the mechanisms of nucleoside-based drug resistance use this reagent to detect the endogenous human protein in cell lysates by WB and to localize it in fixed tissue sections by IHC.