Anti-SLC27A5 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com targets SLC27A5 (Solute Carrier Family 27 Member 5), a liver-enriched membrane protein also known as FATP5 that functions as a bile acid-CoA ligase and long-chain fatty acid transport protein. The reagent is supplied as 100 µl of polyclonal antiserum and is validated for western blot and immunohistochemistry on human and mouse samples.

SLC27A5 plays a pivotal role in hepatic bile acid metabolism and the activation of long-chain fatty acids, making it a relevant marker for studies of liver lipid handling, enterohepatic circulation, and disorders of bile acid homeostasis such as cholestasis and progressive familial intrahepatic cholestasis. Researchers probing hepatocyte physiology, peroxisomal and ER-associated lipid metabolism, or metabolic liver disease can use this reagent to examine endogenous protein expression in tissue sections and lysates, since the antibody recognizes both the human and mouse orthologs.

Produced in rabbit and purified as a polyclonal reagent, this primary antibody is unconjugated and compatible with standard HRP- or fluorophore-based secondary detection systems. Immunohistochemistry signals are expected to localize to hepatocytes, consistent with the protein's known liver-restricted expression pattern.