Anti-SLC26A8 Antibody

The SLC26A8 protein, also called testis anion transporter 1 (TAT1), is a membrane-bound anion exchanger localized to the sperm flagellum. Loss-of-function variants in this gene have been associated with asthenozoospermia and idiopathic male infertility in human patients, making the protein a marker of interest for reproductive biology studies. Antibodies.com offers a rabbit polyclonal antibody raised against the human SLC26A8 sequence that performs in Western blot (WB) and immunohistochemistry (IHC) workflows. The unconjugated reagent is supplied at 100 µl per vial, ready for use with HRP- or fluorophore-conjugated secondary detection reagents. Reactivity has been validated on human tissue, with the antibody commonly applied to formalin-fixed paraffin-embedded testis sections and to whole-cell lysates from spermatogenic cell lines. For long-term performance, aliquot the reagent upon receipt, store at -20 °C, and limit freeze-thaw cycles to preserve binding activity. Researchers working with non-human samples should verify cross-reactivity empirically before drawing species-comparative conclusions.