Anti-SLC25A15 Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets human SLC25A15, the mitochondrial inner membrane ornithine transporter that imports cytosolic ornithine into the mitochondrial matrix for urea cycle processing. Raised in rabbit and supplied as an unconjugated preparation in a 50 µl volume, the reagent is validated for western blot detection of the endogenous transporter in human cell and tissue lysates. The polyclonal format supports recognition of multiple epitopes on the target, which assists detection under varying expression conditions. Mutations in SLC25A15 underlie HHH syndrome (hyperornithinemia-hyperammonemia-homocitrullinuria), and orthogonal antibody reagents like this one are useful for characterizing patient-derived fibroblasts or engineered cell models used to study mitochondrial nitrogen handling. Store the antibody refrigerated at 4°C for short-term use, or aliquot and freeze at -20°C for longer-term stability, and protect from light where appropriate for downstream detection workflows.