Anti-SLC25A13 Antibody

Citrin, the mitochondrial aspartate/glutamate carrier encoded by SLC25A13, is the antigen recognized by this unconjugated rabbit polyclonal antibody. The 100 µl format is supplied as a liquid aliquot for immunodetection workflows that call for an unconjugated primary.

SLC25A13 is a calcium-binding inner membrane transporter involved in the urea cycle, gluconeogenesis, and nucleotide synthesis. Loss-of-function variants are linked to type II citrullinemia (CTLN2) and neonatal intrahepatic cholestasis (NICCD), making reliable detection of the protein relevant to studies of hepatic metabolism, mitochondrial transport, and inherited metabolic disease. Validated applications include western blot (WB) for protein-level confirmation in cell and tissue lysates, and immunohistochemistry (IHC) for spatial localization in formalin-fixed paraffin-embedded sections.

Provided by Antibodies.com as a 100 µl aliquot of rabbit polyclonal antiserum, unconjugated for downstream conjugation to horseradish peroxidase, fluorophores, or biotin as the chosen detection chemistry requires. The reagent is reactive with human samples and is intended for research use in laboratories investigating mitochondrial carrier biology and SLC25A13-associated pathophysiology.