Anti-SLC22A6 Antibody

Rabbit polyclonal IgG antibody targeting SLC22A6, also known as Organic Anion Transporter 1 (OAT1), the basolateral polyspecific organic anion uptake transporter expressed on renal proximal tubule epithelial cells. The unconjugated reagent from Antibodies.com is supplied as a 200 µl liquid aliquot in a vial and is validated for Western blot detection of the human and rat protein in cell and tissue lysates.

Because OAT1 mediates the first step of renal secretion for many organic anion drugs, uremic solutes, and endogenous metabolic conjugates, this antibody is commonly used in transporter pharmacology, drug-drug interaction studies, and nephrotoxicity workflows. In practice it is applied to basolateral membrane preparations, total kidney cortex homogenates, and proximal tubule-derived cell models such as HK-2, where it produces a band near the expected molecular weight of the transporter and is paired with anti-rabbit IgG secondary detection.