Anti-SLC22A2 Antibody

This rabbit polyclonal antibody from Antibodies.com targets SLC22A2, also referred to as OCT2 (organic cation transporter 2), a solute carrier protein predominantly expressed at the basolateral membrane of renal proximal tubule cells. Validated for Western blot and immunohistochemistry on human samples, the unconjugated reagent is supplied as 100 µl of polyclonal serum and recognizes multiple epitopes on the OCT2 transporter, supporting robust detection across expression studies. SLC22A2 mediates cellular uptake of endogenous organic cations and many cationic drugs, and the antibody is frequently used in nephrotoxicity, drug-drug interaction, and renal pharmacokinetics research, where mapping OCT2 distribution helps clarify transporter-mediated clearance mechanisms. Storage at -20 °C in small working aliquots limits freeze-thaw cycles and preserves long-term antibody activity. The polyclonal format and rabbit host allow flexible secondary antibody pairing for chromogenic or fluorescent detection in IHC and standard chemiluminescent or colorimetric Western blot protocols.