Anti-SLC18A2 Antibody

This polyclonal antibody from Antibodies.com targets SLC18A2, the gene encoding vesicular monoamine transporter 2 (VMAT2), the integral membrane transporter that loads monoamines - dopamine, serotonin, norepinephrine, epinephrine, and histamine - into synaptic vesicles of central and peripheral neurons. The reagent is raised in rabbit and supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, in a 100 µl vial sized for western blot and immunohistochemistry workflows on human, mouse, and rat samples. Investigators studying monoaminergic neurotransmission, Parkinson's disease and addiction models, and the action of VMAT2 inhibitors such as reserpine and tetrabenazine use anti-SLC18A2 antibodies to localize transporter expression in brain tissue and to monitor changes in disease or pharmacological paradigms. The 50% glycerol cryoprotectant enables storage at -20 °C in working aliquots, limiting freeze-thaw exposure across multi-week projects, while the polyclonal format provides broader epitope coverage for both native and denatured protein detection.