Anti-SLC18A2 Antibody

The SLC18A2 polyclonal antibody from Antibodies.com is a rabbit-derived IgG reagent raised against the vesicular monoamine transporter 2 (VMAT2), an integral membrane transporter that packages monoamine neurotransmitters, including dopamine, serotonin, norepinephrine, and histamine, into synaptic vesicles. Supplied in unconjugated format for flexible secondary-labeling workflows, the antibody is validated for western blot and immunohistochemistry on human, mouse, and rat samples, supporting cross-species neuroscience and neuropharmacology research.

Investigators use VMAT2 antibodies to map monoaminergic neuron populations in the substantia nigra and ventral tegmental area, evaluate transporter expression in pancreatic beta cells where VMAT2 also contributes to hormone secretion, and probe dopaminergic dysregulation in models of parkinsonism, dystonia, and substance use disorders. The 100 µl volume supports multiple western blot membranes or immunohistochemistry runs when applied at standard working dilutions.

Aliquot the stock upon arrival to limit freeze-thaw cycles of the reagent, and refrigerate working dilutions for short-term use.