Anti-Skp1 p19 Antibody

Skp1 p19 (S-phase kinase-associated protein 1) is the 19 kDa adaptor subunit of the SCF (Skp1-Cullin1-F-box) E3 ubiquitin ligase complex, which drives ubiquitin-dependent proteolysis of cell-cycle regulators including p27, cyclins, and select transcription factors.

This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes native Skp1 p19 in Human, Mouse, and Rat samples, supporting reproducible western blot and immunohistochemistry workflows in fixed or lysed preparations. The antibody is supplied at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% glycerol as a 100 µL vial aliquot, providing ample reagent for multiple blots or staining experiments.

Polyclonal reactivity yields recognition of multiple epitopes on the target, which is useful when signal robustness matters more than absolute monospecificity. Skp1 p19 is broadly expressed and frequently studied in the context of the ubiquitin-proteasome pathway, centriole and centrosome duplication, and kinetochore assembly, making this reagent a practical tool for researchers probing proteostasis, mitotic regulation, and post-translational modification machinery across standard mammalian model systems.