Anti-SKP1 Antibody

SKP1 (S-phase kinase-associated protein 1) is an evolutionarily conserved ~19 kDa adaptor subunit of the SCF E3 ubiquitin ligase complex, where it bridges Cullin-1 scaffolds to substrate-recruiting F-box proteins. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com detects the human target and is supplied as a 200 µl liquid aliquot validated for Western blot applications. Investigators studying ubiquitin-mediated proteolysis, cell cycle progression, and SCF complex assembly use this primary antibody to probe endogenous SKP1 levels in whole-cell lysates. The polyclonal format offers broader epitope coverage than monoclonal alternatives, supporting reliable immunoblotting under standard reducing SDS-PAGE conditions. Refrigerate the antibody upon arrival, protect it from light, and limit freeze-thaw cycles to preserve reagent performance across long-term studies.