Anti-SIX6 Antibody

The Anti-SIX6 Antibody from Antibodies.com is a rabbit polyclonal reagent targeting the SIX6 homeodomain transcription factor, a sequence-specific DNA-binding protein that governs vertebrate eye and anterior pituitary organogenesis. Supplied as 100 µL of unconjugated antisera, this primary antibody is validated for Western Blot and Immunofluorescence workflows across human, mouse, and rat samples. SIX6, also designated OPTX2, regulates retinal progenitor cell maintenance and gonadotrope specification, and has been linked to congenital anophthalmia, microphthalmia, and combined pituitary hormone deficiency in clinical genetics studies. Researchers investigating ocular morphogenesis, neuroendocrine development, or transcription-factor networks can apply this reagent to detect endogenous SIX6 in whole-cell lysates, tissue homogenates, and fixed cryosections. Because the polyclonal host response produces immunoglobulins directed against multiple epitopes on the SIX6 protein, the reagent supports consistent band detection on immunoblots and reproducible nuclear staining patterns in immunofluorescence preparations.