Anti-SIRT7 Antibody

Raised in rabbit against the SIRT7 (Sirtuin 7) protein, this polyclonal reagent from Antibodies.com is supplied as 100 µl of unconjugated antiserum optimized for multiple immunodetection workflows. SIRT7 is the nucleolar-localized member of the mammalian sirtuin family of NAD+-dependent deacetylases, where it modulates ribosomal RNA transcription, controls histone H3 Lys18 acetylation, and deacetylates p53 in response to DNA damage.

Validated applications include Western blot analysis of endogenous SIRT7 in human, mouse, and rat samples, immunofluorescence imaging that reveals characteristic nucleolar staining, and immunohistochemistry on formalin-fixed tissue sections. The unconjugated format permits flexible downstream labeling with HRP, biotin, or fluorophores, while the polyclonal composition recognizes multiple epitopes across the immunogen, supporting robust detection of denatured target on membranes.

Aliquot upon arrival and store refrigerated to preserve activity across repeated freeze-thaw cycles. For research use only.