Anti-SIRT7 Antibody

Raised in rabbit against Sirtuin 7 (SIRT7), this polyclonal Primary Antibody from Antibodies.com recognizes a class III NAD+-dependent deacetylase that localizes primarily to the nucleolus. SIRT7 is studied for its role in ribosomal RNA transcription, chromatin remodeling, ribosome biogenesis, cellular stress responses, and DNA damage repair, with research interest spanning aging, metabolic regulation, and cancer biology.

Supplied unconjugated at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol, the reagent is packaged as a 100 µl vial. It has been validated for Western blot, immunohistochemistry, and immunofluorescence workflows and shows reactivity with human, mouse, and rat samples. The polyclonal format recognizes multiple epitopes across the SIRT7 protein, supporting consistent detection in different sample types.

For handling, aliquot upon receipt and store at -20°C to preserve antibody activity, avoiding repeated freeze-thaw cycles. The 50% glycerol buffer provides additional cryoprotection during frozen storage. Briefly centrifuge the vial before opening to recover liquid from the cap and walls.