Anti-SIRP-α1 / β1 Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets the Signal Regulatory Protein family, binding both SIRP-α1 and SIRP-β1 isoforms commonly expressed on the surface of human myeloid cells. Raised in rabbits and purified as a polyclonal preparation, the antibody is validated for Western blot and ELISA workflows, supporting studies of immune cell signaling, phagocytosis regulation, and tumor microenvironment biology.

Provided as a 100 µl liquid aliquot, the reagent is intended for research use only and should be stored at -20°C in single-use aliquots to preserve activity across repeated freeze-thaw cycles. Its human reactivity profile makes it useful for characterizing SIRP expression in cell lines and primary immune cell cultures, and for probing CD47-SIRP checkpoint pathways relevant to cancer immunotherapy research.